Basic Science of Lp-PLA2
The PLAC Test measures Lp-PLA2 (lipoprotein-associated phospholipase A2) a vascular-specific inflammatory enzyme implicated in the formation of rupture-prone plaque. It is plaque rupture and thrombosis that cause the majority of cardiac events, not stenosis.
| Stable Plaque | Ruptured Plaque |
|---|---|
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Click here to view an annotated bibliography including a substantial body of evidence of over 50 studies and abstracts from peer-reviewed journals and conferences that support Lp-PLA2 as a cardiovascular risk marker in both primary and secondary prevention that provides new information, over and above traditional risk factors.
Click here for a video of a CME event held at the American Heart Association in 2007. This video includes 5 different lectures, and a 10 minute highlight video.